Tuesday, January 24, 2012

Hang out with Obama ... on Google+

Larry Downing/Reuters file

By Rosa Golijan

If you've dreamed about asking President Obama a couple of questions???but the idea of being surrounded by Secret Service agents makes you cringe ??then I've got great news for you. You can hang out with POTUS in a Google+ Hangout soon.

A note on the official YouTube blog explains that Obama will participate in a live-streamed interview on Jan. 30, a few days after the State of the Union address.?This interview will be held in a Google+ Hangout and several individuals will be selected to join the video chat.

The reason these details were revealed on the official YouTube blog is because the way to gain admission to the Google+ Hangout is by submitting video and text questions to the official White House YouTube channel.?Everyone will be invited to vote on their favorite questions and the folks who asked the top-voted ones will be invited to the Google+ Hangout.

Those who don't get to join the actual Hangout will still be able to watch everything live on?WhiteHouse.gov, the White House Google+ page or the White House YouTube channel.

It's worth noting that this particular Google+ Hangout is the first of many. As Kori Schulman, the White House's ?deputy director of outreach for the office of digital strategy,?explained on the White House blog on Friday,?there will be regular "White House Hangouts" with administration officials.

Related stories:

Want more tech news, silly puns or amusing links? You'll get plenty of all three if you keep up with Rosa Golijan, the writer of this post, by following her on?Twitter, subscribing to her?Facebook?posts, or circling her?on?Google+.

Source: http://technolog.msnbc.msn.com/_news/2012/01/23/10216635-hang-out-with-obama-on-google

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Monday, January 23, 2012

Newsmaker: Megaupload a story of Dotcom boom and bust (Reuters)

(Reuters) ? Among the roll-call of hip-hop artists and other celebrities plugging Megaupload.com's digital storage services in an online promotional video, a cameo from the website's founder would have gone unnoticed by many.

As the voiceover boasts of the site's billion users and four percent share of all Internet traffic, a colossal figure clad in black appears in a music studio.

"Bit by bit, it's a hit, it's a hit!" founder Kim Dotcom booms in a slight accent that hints at his German roots.

The hits may have just run out for Dotcom, also known as Kim Schmitz and Kim Tim Jim Investor, who spent his 38th birthday on Saturday in a New Zealand jail after 70 police raided his country estate and cut him out of a safe room he had barricaded himself in.

The Federal Bureau of Investigation, which requested the raid, says Dotcom masterminded a scheme that made more than $175 million in a few short years by copying and distributing music, movies and other copyrighted content without authorization.

Megaupload's U.S. lawyer said the company merely offered online storage, would "vigorously defend itself" and was trying to recover its servers and get back online.

The arrest marks the latest twist in the checkered story of Dotcom, a former hacker who got his first computer at nine before going on to build an Internet fortune and friendships with music stars including Alicia Keys, Will.i.am and P.Diddy who appeared on the Megaupload.com promo video.

EARLY STARTER

Born in the German city of Kiel, Dotcom -- who was then known as Schmitz -- grew up in northern Germany.

As a child, he made copies of computer games to sell to his friends, and in the early days of the Internet, began hacking into computers via telephones, according to reputed German daily Die Welt.

Schmitz has made no secret of his controversial past as a cyber-raider, hacking into computer networks at NASA, the Pentagon and at least one major bank.

As the hacker pioneer generation came of age, so did Schmitz. After being convicted of computer hacking in 1998, he made a fortune providing computer security consulting and venture capital investment via the firm Kimvestor.

According to German magazine Der Spiegel, Schmitz once boasted he would become one of the richest men in the world. How was he so sure? "I'm smarter than Bill Gates," he said.

Schmitz, who also called himself Kimble after the wrongly convicted doctor-on-the-run in the film "The Fugitive," became well known for his lavish lifestyle as much as his computer skills.

He briefly became a fixture in Germany's nouveau riche party scene and made his own film, shot with a hand-held camera, Kimble Goes Monaco. The hulking Schmitz -- reportedly two meters tall and weighing more than 130 kg -- was often shown in Germany's tabloid press with fast cars and a model on his arm.

Schmitz's website at one point featured photographs of him racing cars, shooting an assault rifle and flying around the world in his private jet on lavish vacations.

"I have a different attitude towards money than those who rather hoard it," he said during an appearance on the Harald Schmidt Show, a popular late-night talk show in Germany. "I would rather spend it and have a lot of fun."

A documentary about the outlaw Gumball 3000 road race of 2001 by German TV station RTL filmed Schmitz driving the Russian leg of the rally in excess of 240 kph (150 mph) in a 480-horsepower Mercedes sedan, and then laughing when an opponent is pulled over by police in Finland. "Our competition is out of the way!" he says in jubilation.

Schmitz liked promoting himself through stunts such as offering up to $10 million for information leading to the arrest of Osama bin Laden in the wake of terror attacks against the United States.

THE NAME'S DOTCOM. KIM DOTCOM

But in 2002, he was convicted in what was then the largest insider-trading case in German history.

Prosecutors said Schmitz bought shares in an online business and drove up the share price by announcing plans to invest millions to rescue the company from insolvency. After selling his shares for a profit, he fled to Thailand, was arrested and deported.

A Munich court sentenced the then 28-year-old to 20 months probation and a 100,000-euro fine.

After his conviction, Schmitz disappeared from public view, reappearing a couple of years ago in New Zealand, having legally changed his name to Dotcom.

He and his family moved into a multimillion dollar mansion outside Auckland and were granted residency after promising to invest at least NZ$10 million ($8 million) in New Zealand.

The leased 20-hectare property, set in rolling hills northwest of Auckland, is one of the largest and most expensive in the country, featuring manicured lawns, fountains, pools, palm-lined paths and extensive security.

In an interview with the New Zealand Herald Newspaper last year, Dotcom said residency would allow him, his wife, Mona, and their three children to live in a country that would become a "rare paradise on Earth."

"I might be one of the most flamboyant characters New Zealand has ever seen but my intentions are good and I would like to see New Zealand flourish to its fullest potential," he said.

Dotcom reportedly paid $500,000 for a massive New Year's Eve fireworks display over Auckland which he and Mona watched from their private helicopter.

The FBI estimates that Dotcom personally made around $115,000 a day during 2010 from his empire. The list of property to be forfeited, including almost 20 luxury cars, one of them a pink Cadillac, hints at a lavish lifestyle which may be about to be put on hold.

Dotcom and three fellow accused will appear in a New Zealand court on Monday and face extradition to the United States. ($1 = 1.2433 New Zealand dollars)

(Reporting by Lincoln Feast in SYDNEY and Sarah Marsh in FRANKFURT; Additional reporting by Peter Maushagen in FRANKFURT, Mantik Kusjanto in WELLINGTON and Brian Rohan in BERLIN; Editing by Nick Macfie)

Source: http://us.rd.yahoo.com/dailynews/rss/tech/*http%3A//news.yahoo.com/s/nm/20120122/wr_nm/us_internet_megaupload

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Sunday, January 22, 2012

S.C. Primary: Newt Gingrich Looks To 'Make History'

NORTH CHARLESTON, S.C. -- Newt Gingrich is feeling it. Having slugged his way to the lead for the second time, the former House speaker spies victory in South Carolina, a win he has said repeatedly will "make history" and, ultimately, hand him the Republican nomination for president.

The former boast seemed as fanciful as Gingrich's Mars program a week ago. Today, it's conventional wisdom.

In Orangeburg on Friday, speaking to a two-room overflow crowd in a shopping mall, Gingrich held up and knocked down the gallery of elitist thugs he holds responsible for the wayward course of America: "anti-religious judges," "academic journalists," bureaucrats, Hollywood and, of course, "Obama" -- Gingrich never calls him "President Obama."

And Juan Williams. Gingrich paused to take time to toy with Williams, the FOX commentator who last Monday -- in the pivotal moment of the campaign here -- had questioned whether Gingrich was seeking to ?belittle people? by talking about the "food stamp president" and by suggesting that urban youths do janitorial work in schools.

Gingrich's sneering, "Well ... Juan," reply in that debate brought the crowd to its feet and launched him toward the lead. A much more sophisticated southern strategy than the one employed by his party in the 1970s, it nevertheless imparted a simple message, that Gingrich is the candidate who can articulately and passionately channel your rage.

"The man is a figher," South Carolina House Speaker Bobby Harrell told a crowd of supporters in a hangar of the USS Yorktown Friday. "He doesn't back down and that's what we need in Washington."

Harrell had previously been a Rick Perry backer, he told the crowd. But after the Texas governor dropped out, he switched to Gingrich, rallied by his fierce debate performances.

As if constructing a metaphor for his own campaign, Gingrich's day began with a cancellation due to lack of public interest, veered into a bizarre and extended visit to a hospital's emergency department, and ended with a packed and energetic rally.

The mood couldn't have been different for Mitt Romney, who'd hoped to come out of South Carolina with his third straight victory, but may improbably wind up instead with a record of 1-2, now that final vote tallies show he actually lost Iowa to Rick Santorum (who is still running, for what it's worth).

"When I was in Iowa I joked that the corn counted as an amber wave of grain," he told a crowd of about 300 people, after he quoted "America the Beautiful" on Friday morning. "That may account for my slim, uh, defeat there. I used to say that accounted for an eight-point win, but I had to change my rhetoric in the last couple of days."

He dropped the joke from a speech in North Charleston in the afternoon. There's little to laugh about for the former Massachusetts governor, unless he's chuckling awkwardly after saying he'd "maybe" release more than one year of tax returns next April.

South Carolinians say their state picks presidents. Mitt Romney used to say so too.

In South Carolina, six of the seven most recent surveys conducted this week now show Gingrich running slightly ahead of Romney, evidence of a collapse for the record books. The just-released Clemson University Palmetto Poll, conducted on Wednesday and Thursday nights, shows Gingrich leading Romney by a 32 percent to 26 percent margin, with Ron Paul and Rick Santorum running far behind (at 11 percent and 9 percent, respectively).

The HuffPost Pollster chart, based on all available public polls, shows a 13 percentage point jump for Gingrich in the last week. He now runs ahead of Romney by nearly five points (33.9 to 29.0 percent), followed by Paul running a distant third (at 13.9 percent).

The chart also shows support for Santorum plummeting about as much as support for Gingrich has increased, from a high of more than 22 percent just after the Iowa caucuses to just 8.4 percent now.

The latest Public Policy Polling (PPP) survey found, for example, that Santorum supporters choose Gingrich more often than Romney as their second choice (40 to 24 percent).

On Friday, Romney began to seriously dial back expectations. He said he had an "uphill battle" in South Carolina anyway, because Gingrich is from the neighboring state, and that it's more important to win delegates, who will make the eventual choice at the Republican National Convention in August should the race still be undecided.

"I want as many delegates as I can get -- I want the most delegates coming out of South Carolina," he told reporters in Gilbert. "But I don?t know what the numbers will be."

Former New Hampshire Gov. John Sununu, a chief Romney surrogate, made the same effort on Friday, telling reporters he expects a "long slog."

That long slog could drag all the way to Tampa, where Republicans hold their political convention in late summer. As long as Ron Paul continues pulling significant support, and a conservative alternative remains viable -- which, in the age of Citizens United, means having just one deep-pocked casino mogul, for instance -- it'll be difficult for any one candidate to lock up a majority of delegates.

That could mean a "brokered convention," where a candidate is chose by party elites behind closed doors. It could be anybody. "I've been talking quietly to the most powerful, I think, conservative movers-and-shakers in Washington over the past couple weeks, trying to get their read," MSNBC host Joe Scarborough, a former congressman, said Friday. "Every single one I've spoken to is trying to figure out a way to get to a brokered convention." (Of course, movers and shakers would enjoy a brokered convention because they'd be the ones doing the brokering.)

Whatever the outcome Saturday evening, it's clear that it won't be the knock-out blow Romney had hoped to deliver before turning his attention to President Obama. Instead, he'll limp to Florida, where he and his super PAC have been plastering television sets with ads long before other candidates had been able to get up and running.

Florida's primary, the Tuesday after next, will be followed Feb. 4 with a caucus in Nevada. A month later is Super Tuesday.

If Romney loses Saturday, it'll also be a stinging rebuke to the state's Tea Party-backed governor Nikki Haley. Campaigning with Romney Friday, she was off her game. "This current president wants to weaken our military and President Obama wants to strengthen our military and will never apologize for it," Haley said, according to a Patch report

"Oh, no. McCain did that two weeks ago, and, I just turned 40 today," she said.

Jon Ward and Howard Fineman contributed reporting

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Source: http://www.huffingtonpost.com/2012/01/21/south-carolina-primary-2012_n_1220391.html

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Scientists pause research with lab-bred bird flu (AP)

WASHINGTON ? The scientists who created easier-to-spread versions of the deadly bird flu say they're temporarily halting more research, as international specialists debate what should happen next.

Last month, U.S. officials had urged two labs not to publicly reveal how they brewed the new viruses, for fear would-be bioterrorists might copy them. Critics also worried a lab accident might allow the strains to escape.

The viruses are held in high-security labs in the U.S. and the Netherlands. They were created to help learn how bird flu might mutate to become a bigger threat to people. But in a letter Friday to the journals Science and Nature, the scientists said they would "pause" additional research for 60 days as world health officials debate how to learn from the work, safely.

Source: http://us.rd.yahoo.com/dailynews/rss/health/*http%3A//news.yahoo.com/s/ap/20120120/ap_on_he_me/us_med_bird_flu

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Saturday, January 21, 2012

Guillard knows he can?t slip again tomorrow night on FX

Melvin Guillard doesn't want to go the way of George Sotiropoulos, Anthony Pettis and Evan Dunham.

Last year was a horror show for those guys. On the verge of getting a title shot, all three suffered a loss or two that sent that sent them tumbling down the lightweight ladder.

Guillard faces Jim Miller tomorrow night on FX (9 p.m. ET/6 p.m. PT), with both fighters facing the same fate if they lose - at least another year before they sniff a title shot.

Guillard (29-9-2, 10-5 UFC) was hot as a pistol before UFC 136 in October, but lost his shot at Frank Edgar with a 47 second submission loss at the hands of Joe Lauzon. He knows this Miller fight is make or break time.

"It was kinda dumb, but I am young enough to learn as long as realize the mistake. I made the mistake, it didn't just happen," Guilard said referencing the loss to Lauzon. "I know that but I also know I'm still one of the best fighters in the division. But I am ready for this fight with Miller. He's a top guy, maybe the No. 3 or No. 4 in the division, and if I perform like I can do, I think it will be hard for people to say that I didn't deserve a UFC title shot."

Guillard is managing the delicate balance between fighter under control, but not losing his explosiveness

"It's not going to affect my style of fight, just so you guys know. I'm still going to go in and be the fast, explosive kid that I am. But right now, I just want to stay focused and grounded," said Guillard.

Miller is no easy prey and he enters the fight with the same motivation. He's coming off a rough loss to Ben Henderson. Miller (20-3, 9-2 UFC) fought with a flawed strategy and got lit up by Henderson, who locked up a title shot with the victory.

Source: http://sports.yahoo.com/blogs/mma-cagewriter/guillard-knows-t-slip-again-tomorrow-night-fx-183311796.html

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FDA clears safety test to screen Tysabri patients

(AP) ? The Food and Drug Administration on Friday approved a new diagnostic test to help identify patients who have an increased risk of developing a rare brain infection while taking Biogen Idec's multiple sclerosis drug Tysabri.

Tysabri is one of a handful of drugs used to control multiple sclerosis, a debilitating disease in which the body attacks its own nervous system. Prescribing of the drug has been tightly controlled by the FDA because of a rare infection that causes inflammation of the brain, known as multifocal leukoencephalopathy, or PML. Currently there is no treatment or cure for PML, which is usually fatal.

The newly approved Stratify JCV test is designed to detect a common virus that increases the likelihood of developing the brain infection. The John Cunningham virus is harmless in most people, but can become dangerous in patients taking immune system-suppressing drugs like Tysabri.

Doctors can use the results of the blood-based test, combined with facts about the patient's medical history, to determine whether they are at risk of developing the brain infection. Other factors that influence a patient's risk include how long they've been taking Tysabri and whether they've previously taken other medications that weaken the immune system.

The test was developed by Quest Diagnostics.

The FDA also updated Tysabri's label to specify that patients who test positive for the virus have a higher risk of developing PML.

"This label change marks an important advance in assisting people with MS and their physicians to make better-informed decisions concerning the challenges of balancing effectiveness with safety," said Dr. Nicholas LaRocca, vice president of the National MS Society.

Tysabri was temporarily pulled from the market shortly after its launch in 2005 after three patients taking the drug developed PML. FDA allowed the drug back on the market the following year but under a restricted distribution program. Only doctors and pharmacies registered with the company's distribution program are permitted to prescribe and dispense the drug.

Biogen, based in Weston, Mass., sells Tysabri through a partnership with Elan Corp., an Irish drugmaker.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2012-01-20-Biogen%20Drug-Safety%20Test/id-7ff4f61cbcc14d5cab6576d5b2d13602

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Friday, January 20, 2012

How drugs get those tongue-twisting generic names

ScienceDaily (Jan. 18, 2012) ? Oseltamivir. Esomeprazole. Trastuzumab. Where do drugs get those odd-sounding generic names? The answers are in the current issue of Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, the world's largest scientific society, which explains the logic behind the tongue-twisters.

C&EN Associate Editor Carmen Drahl explains that until 1961 there was no standard for assigning drugs generic names, which are different from brand names like Tamiflu (oseltamivir), Nexium (esomeprazole) and Herceptin (trastuzumab). That's when three medical organizations created the U.S. Adopted Names (USAN) Council to assign simplified alternatives to the unwieldy proper names the International Union of Pure & Applied Chemistry gives to molecules. For instance, under USAN's guidance, "cis-8-methyl-N-vanillyl-6-nonenamide" becomes "zucapsaicin." The council recommends generic names to an international agency of the World Health Organization. The tongue-twisting words the USAN Council creates are products of "stems" that describe a drug's characteristics, which Drahl likens to the Latin and Greek roots of many English words.

Drahl writes that these stems describe everything from a drugs' function to its shape. For instance, the "-prazole" ending of Nexium's generic name, esomeprazole, reveals that it is a type of antiulcer medication. Similar drugs will have the same stems in their names, allowing those familiar with the stems to crack the code. The USAN Council is careful to avoid words that are difficult to pronounce in foreign languages or that may have other meanings abroad. Sometimes, Drahl notes, a generic name will also include hints about its developer that a drug company has suggested to the council, as in carfilzomib, which recognizes molecular biologist Philip Whitcome and his wife Carla.

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The above story is reprinted from materials provided by American Chemical Society.

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Journal Reference:

  1. Carmen Drahl. Where Drug Names Come From: Behind every generic name lies a specific process. Chemical & Engineering News, 2012; 90 (3): 36-37 [link]

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2012/01/120118112009.htm

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